2Division of Anaesthesia, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Royal Brompton Hospital, Guy’s and St Thomas’ NHSFT, London, United Kingdom
3Faculty of Medicine, Imperial College London, United Kingdom
4Chelsea and Westminster NHS Foundation Trust, London, United Kingdom; Division of Anaesthesia, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Royal Brompton Hospital, Guy’s and St Thomas’ NHSFT, London, United Kingdom; Faculty of Medicine, Imperial College London, United Kingdom
Abstract
This review aims to explore the relationship between taste, hunger, and satiety and their influence on outcomes for patients in intensive care units (ICUs). A literature search was conducted using MeSH (Medical Subject Headings) and key terms across PubMed Online, Google Scholar, the Cochrane Library, Embase, and UpToDate between February 28, 2003 and May 19, 2023, following guidance from the EQUATOR (Enhancing the Quality and Transparency of Health Research) network. Inclusion criteria comprised English-language articles reporting outcome studies of ICU patients related to taste, hunger, or satiety, stratified by acute or recovery phases. The search yielded 943 citations. After reviewing abstracts, 10 full-text articles were retrieved and included, though the quality of evidence was limited to observational studies. Findings indicate that patients commonly experience early satiety and decreased appetite during the acute phase of critical illness, which typically improves by three months post-ICU. However, appetite dysregulation may persist beyond this period. Reduced appetite, a common feature of Post-Intensive Care Syndrome (PICS), was associated with long-term low mood. While taste alterations were reported, no studies addressed their restoration or impact. These findings highlight the need for further primary research into taste alterations and their effects on the patient experience among critical illness survivors. This review underscores the limited research available on how changes in taste, hunger, and satiety affect ICU survivors and suggests that additional studies are necessary to further explore these aspects.