Journal of Critical and Intensive Care
2020 , Vol 11 (Supplement)
Blood Purification Treatments in COVID-19
1Erciyes University, Department of Internal Medicine, Division of Critical Care, Kayseri, Turkey
DOI :
10.37678/dcybd.2020.2436
Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) emerged for the first time in Wuhan, China,
in December 2019. These viruses mainly cause respiratory and intestinal infections and induce a variety of
clinical manifestations (1, 2). High virus titer and the subsequent strong inflammatory cytokine and chemokine
responses are related to the high morbidity and mortality observed during the pathogenic HCoV infection.
Blood purification system including plasma exchange, adsorption, perfusion, blood/plasma filtration, etc., can
remove inflammatory factors, block the "cytokine storm", to reduce the damage of inflammatory response
to the body. This therapy can be used for severe and critical patients in the early and middle stages of the
disease (3). We recommend not using Extracorporeal treatments based on cytokine and / or endotoxin removal
routinely in patients infected with COVID-19 due to insufficient studies (4).
Keywords :
COVID-19, Blood purification therapy, sepsis, SARS-CoV-2