Material and Methods: In this study, patients who were non-neutropenic and developed candidemia in the ICU of Turkey Advanced Specialty Training and Research Hospital between May 2016 and May 2017 were retrospectively evaluated. Patients who stayed (±7 days) in the same ICU, with an APACHE-II score of ±1, during the same period were included as the control group.
Results: Candidemia was detected in 29 adults within 1 year. In total, 11 of the candidemia cases were females (37.9%) and 18 were males (62.1%); mean patient age was 62.0 years. The most common causative agent was Candida albicans (58.6%). In both groups, the three most common accompanying bacterial infections were Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae. Moreover, 30-day mortality was 51.7%. The mean central venous catheter day, the mean mechanical ventilator day, and the length of hospital stay were longer in the candidemia group (p<0.05). The use of meropenem and teicoplanin was statistically significantly more common in the candidemia group (p<0.05).
Conclusion: In this study, we found that the most common Candida species in non-neutropenic patients was C. Albicans, and the most common risk factor for candidemia was the use of meropenem and teicoplanin. The-refore, we believe further studies are needed to evaluate different groups of antibiotics as risk factors for candidemia.
Keywords : Candidemia, sepsis, intensive care units, neutropenia